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Meningitis Viral 2 ELITe MGB® Panel

Enterovirus, parechovirus, and adenovirus are common causes of viral meningitis, especially in neonates and young children. Meningitis induced by these viruses can present similar symptoms to bacterial meningitis. Rapid detection with molecular testing methods is crucial to identify the viral agent involved, rule out a bacterial infection and provide an adapted treatment. Meningitis Viral 2 ELITe MGB® Panel is a one-step, reverse-transcription and real-time PCR multiplex assay designed for the detection of enterovirus RNA, parechovirus RNA and adenovirus DNA specific genes. The assay is CE-IVD validated on cerebrospinal fluid samples, in combination with ELITe InGenius®, a fully automated sample-to-result solution.

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Benefits

Conserved targets
  • Enterovirus: domains IV & V of 5’UTR RNA region
  • Parechovirus: 5’UTR RNA region
  • Adenovirus: capsid protein gene DNA
  • Internal control: Brome mosaic virus DNA sequence
Best-in class PCR technology
  • TaqMan probes designed with Minor Groove Binder technology
Sample
  • Cerebrospinal fluid
Integrated workflow
  • Fully automated process for extraction, amplification and result analysis with ELITe InGenius
High performance
  • Enterovirus: 100% clinical sensitivity and 100% clinical specificity
  • Parechovirus: 100% clinical sensitivity and 100% clinical specificity
  • Adenovirus: 100% clinical sensitivity and 100% clinical specificity
Eluate storage
  • Additional testing including multiple PCR from the same eluate, retesting or archiving
Minimal hands-on time
  • Less than 2 minutes per sample from extraction to result analysis
Complete meningitis menu
  • Meningitis Viral 1 ELITe MGB® Panel (HSV1, HSV2, VZV) and Meningitis Bacterial ELITe MGB® kit (N.meningitides, S. pneumoniae, H. influenzae, H. influenzae type B)

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