BCR-ABL P210 ELITe MGB^® Kit

The product of the Philadelphia translocation, the BCR/ABL oncogene P210 isoform, is typically found in chronic myelogenous leukemia, and in acute lymphoid and myeloid leukemia, causing the cells to divide uncontrollably and inducing severe outcomes among patients. Detection and quantification of P210 BCR-ABL fusion gene, by molecular methods, is crucial for patient management, to initiate the appropriate treatment, measure the response to therapy and predict relapse BCR-ABL P210 ELITe MGB^® Kit is a real-time PCR assay for the quantification of the mRNA of the BCR-ABL rearrangement, t(9;22) translocation of the Philadelphia chromosome, isoform P210 compared to the mRNA of the gene coding the kinase protein Abelson (ABL) mRNA. The assay is validated on Mononuclear Cells from human Peripheral Blood or Bone Marrow in combination with ELITe InGenius^®, a fully automated sample-to-result solution..